Cadps2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cadps2
Ca2+-dependent activator protein for secretion 2
MGI:2443963

40 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cadps2^{em1(IMPC)Rbrc}/Cadps2^{em1(IMPC)Rbrc} C57BL/6NJcl-Cadps2^{em1(IMPC)Rbrc}/Rbrc	abnormal circulating alkaline phosphatase level	J:211773
	abnormal duodenum morphology	J:211773
	abnormal ileum morphology	J:211773
	abnormal jejunum morphology	J:211773
	abnormal lymph node morphology	J:211773
	abnormal mean corpuscular hemoglobin	J:211773
	abnormal pancreas morphology	J:211773
	abnormal salivary gland morphology	J:211773
	enlarged lymph nodes	J:211773
	increased circulating amylase level	J:211773
Cadps2^tm1Bros/Cadps2^tm1Bros Not Specified	abnormal pancreatic beta cell physiology	J:131014
	abnormal pancreatic somatostatin secretion	J:131014
	decreased insulin secretion	J:131014
	impaired glucose tolerance	J:131014
	increased glucagon secretion	J:131014
	increased insulin sensitivity	J:131014
Cadps2^tm1Tfr/Cadps2⁺ C57BL/6-Cadps2^tm1Tfr	abnormal maternal nurturing	J:121256
Cadps2^tm1Tfr/Cadps2⁺ C57BL/6-Cadps2^tm1Tfr	decreased exploration in new environment	J:121256
Cadps2^tm1Tfr/Cadps2^tm1Tfr C57BL/6-Cadps2^tm1Tfr	abnormal brain interneuron morphology	J:121256
	abnormal brain morphology	J:121256
	abnormal cerebellar granule cell migration	J:120106
	abnormal cerebellum external granule cell layer morphology	J:120106
	abnormal cerebellum fissure morphology	J:120106
	abnormal cerebellum morphology	J:120106
	abnormal circadian behavior	J:121256
	abnormal emotion/affect behavior	J:121256
	abnormal maternal nurturing	J:121256
	abnormal neuron specification	J:120106
	abnormal optokinetic reflex	J:120106
	abnormal paired-pulse facilitation	J:120106
	abnormal Purkinje cell dendrite morphology	J:120106
	abnormal response to novel object	J:121256
	abnormal sleep pattern	J:121256
	abnormal social investigation	J:121256
	abnormal social/conspecific interaction behavior	J:121256
	abnormal spatial reference memory	J:121256
	decreased body weight	J:121256
	decreased exploration in new environment	J:121256
	decreased Purkinje cell number	J:121256
	hyperactivity	J:121256
	impaired coordination	J:120106
	increased anxiety-related response	J:121256

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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