Rasgef1b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rasgef1b
RasGEF domain family, member 1B
MGI:2443755

12 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rasgef1b^em1(IMPC)J/Rasgef1b^em1(IMPC)J C57BL/6NJ-Rasgef1b^em1(IMPC)J/Mmjax	abnormal behavior	J:211773
	decreased prepulse inhibition	J:211773
	decreased thigmotaxis	J:211773
Rasgef1b^tm1.1Sila/Rasgef1b^tm1.2Sila Tg(CMV-cre)1Cgn/0 involves: BALB/cJ * C57BL/6	abnormal microglial cell morphology	J:344440
	abnormal tumor necrosis factor level	J:344440
	anhedonia	J:344440
	decreased anxiety-related response	J:344440
	decreased depression-related behavior	J:344440
	decreased thigmotaxis	J:344440
	enhanced coordination	J:344440
	impaired active avoidance behavior	J:344440
	increased locomotor activity	J:344440
	increased stereotypic behavior	J:344440

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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