Vps18 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vps18
VPS18 CORVET/HOPS core subunit
MGI:2443626

16 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vps18^tm1.1Wtao/Vps18^tm1.1Wtao Tg(Nes-cre)1Kln/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL	abnormal autophagy	J:186307
	abnormal cerebellum morphology	J:186307
	abnormal hippocampus CA3 region morphology	J:186307
	abnormal hippocampus morphology	J:186307
	abnormal neuron physiology	J:186307
	abnormal neuronal migration	J:186307
	decreased body size	J:186307
	decreased brain size	J:186307
	increased neuron apoptosis	J:186307
	neurodegeneration	J:186307
	postnatal growth retardation	J:186307
	postnatal lethality, complete penetrance	J:186307
	small cerebellum	J:186307
Vps18^tm1.1Wtao/Vps18^tm1.1Wtao Tg(Pcp2-cre)2Mpin/0 B.129-Vps18^tm1.1Wtao Tg(Pcp2-cre)2Mpin	decreased Purkinje cell number	J:186307
	normal nervous system phenotype	J:186307
Vps18^tm1Wtao/Vps18^tm1Wtao involves: 129S6/SvEvTac * C57BL/6	preweaning lethality, complete penetrance	J:186307

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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