Fancm Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fancm
Fanconi anemia, complementation group M
MGI:2442306

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fancm^em1Qsh/Fancm^em1Qsh C57BL/6-Fancm^em1Qsh	abnormal seminiferous tubule morphology	J:301639
	abnormal spermatid morphology	J:301639
	normal hematopoietic system phenotype	J:301639
	increased cellular sensitivity to DNA damaging agents	J:301639
	increased male germ cell apoptosis	J:301639
	male infertility	J:301639
	normal neoplasm	J:301639
	seminiferous tubule degeneration	J:301639
Fancm^tm1.1Htr/Fancm⁺ involves: C57BL/6 * FVB	increased tumor incidence	J:151714
Fancm^tm1.1Htr/Fancm⁺ involves: C57BL/6 * FVB	premature death	J:151714
Fancm^tm1.1Htr/Fancm^tm1.1Htr involves: C57BL/6 * FVB	abnormal ovary morphology	J:151714
	abnormal seminiferous tubule morphology	J:151714
	abnormal spermatogonia morphology	J:151714
	azoospermia	J:151714
	decreased mature ovarian follicle number	J:151714
	elevated level of mitotic sister chromatid exchange	J:151714
	normal hematopoietic system phenotype	J:151714
	increased hepatoma incidence	J:151714
	increased Leydig cell number	J:151714
	increased tumor incidence	J:151714
	premature death	J:151714
	small testis	J:151714
	transmission ratio distortion	J:151714

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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