60 phenotypes from 11 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dclre1cm1Brck/Dclre1cm1Brck involves: C3H * C57BL/6	absent B cells	J:207533
	absent T cells	J:207533
Dclre1cm1Brck/Dclre1cm1Brck involves: C57BL/6	absent B cells	J:207533
	absent CD4-positive, alpha-beta T cells	J:207533
	absent CD8-positive, alpha-beta T cells	J:207533
	decreased DN1 thymic pro-T cell number	J:207533
	decreased DN4 thymocyte number	J:207533
	decreased double-positive T cell number	J:207533
	decreased pre-B cell number	J:207533
	normal immune system phenotype	J:207533
Dclre1cm1Btlr/Dclre1cm1Btlr C57BL/6J-Dclre1cm1Btlr	decreased B cell number	J:217790
	decreased IgM level	J:217790
	decreased response to antigen	J:217790
	decreased single-positive T cell number	J:217790
	decreased T cell number	J:217790
	impaired humoral immune response	J:217790
	increased macrophage cell number	J:217790
	increased neutrophil cell number	J:217790
	increased NK cell number	J:217790
Dclre1cM2Btlr/Dclre1cM2Btlr C57BL/6J-Dclre1cM2Btlr	decreased CD4-positive, alpha-beta T cell number	J:265131
	decreased CD8-positive, naive alpha-beta T cell number	J:265131
	decreased single-positive T cell number	J:265131
	decreased T cell number	J:265131
	increased body weight	J:265131
	increased central memory CD8 positive, alpha-beta T cell number	J:265131
	increased effector memory CD4-positive, alpha-beta T cell number	J:265131
	increased effector memory CD8-positive, alpha-beta T cell number	J:265131
Dclre1cm3Btlr/Dclre1cm3Btlr C57BL/6J-Dclre1cm3Btlr	decreased B cell number	J:265132
	decreased B-1 B cell number	J:265132
	decreased body size	J:265132
	decreased body weight	J:265132
	decreased CD4-positive, alpha-beta T cell number	J:265132
	decreased CD8-positive, alpha-beta T cell number	J:265132
	decreased CD8-positive, naive alpha-beta T cell number	J:265132
	decreased NK T cell number	J:265132
	decreased single-positive T cell number	J:265132
	decreased systemic arterial systolic blood pressure	J:265132
	decreased T cell number	J:265132
	increased central memory CD4-positive, alpha-beta T cell number	J:265132
	increased effector memory CD4-positive, alpha-beta T cell number	J:265132
	increased effector memory CD8-positive, alpha-beta T cell number	J:265132
Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa involves: 129S6/SvEvTac * C57BL/6	arrested B cell differentiation	J:80995
	arrested T cell differentiation	J:80995
Dclre1ctm1.1Jpdv/Dclre1ctm1.1Jpdv involves: 129P1/ReJ	abnormal B cell differentiation	J:137743
	abnormal T cell receptor V(D)J recombination	J:194422
	arrested T cell differentiation	J:137712
Dclre1ctm1Fwa/Dclre1ctm1Fwa involves: 129S6/SvEvTac	abnormal T cell receptor beta chain V(D)J recombination	J:147864
	absent B cells	J:147864
	arrested B cell differentiation	J:147864
	decreased CD4-positive, alpha-beta T cell number	J:147864
	decreased CD8-positive, alpha-beta T cell number	J:147864
	decreased double-positive T cell number	J:147864
	decreased thymocyte number	J:147864
	increased cellular sensitivity to gamma-irradiation	J:147864
	induced chromosome breakage	J:147864
	spleen hypoplasia	J:147864
Dclre1ctm1Fwa/Dclre1ctm1Fwa involves: 129S6/SvEvTac * C57BL/6	absent immature B cells	J:80995
	arrested B cell differentiation	J:80995
	arrested T cell differentiation	J:80995
	chromosomal instability	J:80995
	decreased thymocyte number	J:80995
	increased cellular sensitivity to ionizing radiation	J:80995
Dclre1ctm1Jsek/Dclre1ctm1Jsek involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal immunoglobulin heavy chain V(D)J recombination	J:147864
	abnormal T cell receptor beta chain V(D)J recombination	J:147864
	decreased B cell number	J:147864
	decreased CD4-positive, alpha-beta T cell number	J:147864
	decreased CD8-positive, alpha-beta T cell number	J:147864
	decreased double-positive T cell number	J:147864
	decreased pre-B cell number	J:147864
	decreased thymocyte number	J:147864
	increased cellular sensitivity to gamma-irradiation	J:147864
	increased pro-B cell number	J:147864
	induced chromosome breakage	J:147864
	spleen hypoplasia	J:147864
Dclre1ctm2.1Jpdv/Dclre1ctm2.2Jpdv Tg(Cr2-cre)3Cgn/0 involves: 129S2/SvPas * C57BL/6	abnormal class switch recombination	J:153841
	normal immune system phenotype	J:153841
Dclre1ctm2.2Jpdv/Dclre1ctm2.2Jpdv B6.129S2-Dclre1ctm2.2Jpdv	abnormal mononuclear cell morphology	J:153841
	absent immature B cells	J:153841
	arrested B cell differentiation	J:153841
	arrested T cell differentiation	J:153841
	decreased CD4-positive, alpha-beta T cell number	J:153841
	decreased CD8-positive, alpha-beta T cell number	J:153841
	decreased double-positive T cell number	J:153841
	decreased mature B cell number	J:153841
	decreased splenocyte number	J:153841
	decreased thymocyte number	J:153841
Dclre1ctm2Mcow/Dclre1ctm2Mcow involves: 129/Sv * C57BL/6	abnormal cell physiology	J:96535
	abnormal leukocyte physiology	J:96535
	abnormal lymph node morphology	J:96535
	abnormal spleen B cell follicle morphology	J:96535
	absent thymus cortex	J:96535
	arrested B cell differentiation	J:96535
	arrested T cell differentiation	J:96535
	decreased B cell proliferation	J:96535
	decreased lymphocyte cell number	J:96535
	decreased T cell proliferation	J:96535
	decreased thymocyte number	J:96535
	decreased thymus weight	J:96535
	increased cellular sensitivity to ionizing radiation	J:96535
	small lymph nodes	J:96535
	small spleen	J:96535