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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tbl1xr1
Tbl1x/y related 1
MGI:2441730
36 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ighg1tm1(cre)Cgn/Ighg1+
Tbl1xr1tm1c(EUCOMM)Hmgu/Tbl1xr1tm1c(EUCOMM)Hmgu
involves: 129P2/OlaHsd * C57BL/6J 		abnormal B cell differentiation J:292118
abnormal spleen morphology J:292118
Ighg1tm1(cre)Cgn/Ighg1+
Tbl1xr1tm1.1Meln/Tbl1xr1+
involves: 129P2/OlaHsd * C57BL/6J 		abnormal B cell differentiation J:292118
abnormal spleen morphology J:292118
Tbl1xr1tm1.1Arte/Tbl1xr1tm1.1Arte
Tg(Fabp4-cre)1Rev/0
involves: C57BL/6 		abnormal adipose tissue physiology J:198124
abnormal white adipose tissue morphology J:198124
impaired glucose tolerance J:198124
impaired lipolysis J:198124
increased abdominal fat pad weight J:198124
increased body weight J:198124
increased circulating leptin level J:198124
increased inguinal fat pad weight J:198124
increased liver triglyceride level J:198124
increased skeletal muscle triglyceride level J:198124
increased susceptibility to diet-induced obesity J:198124
increased total body fat amount J:198124
increased white fat cell number J:198124
increased white fat cell size J:198124
insulin resistance J:198124
Tbl1xr1tm1b(EUCOMM)Hmgu/Tbl1xr1+
C57BL/6N-Tbl1xr1tm1b(EUCOMM)Hmgu/Ieg 		abnormal liver morphology J:211773
abnormal startle reflex J:211773
absent vibrissae J:211773
decreased circulating HDL cholesterol level J:211773
enlarged cecum J:211773
enlarged liver J:211773
enlarged ovary J:211773
increased blood urea nitrogen level J:211773
increased circulating insulin level J:211773
increased circulating phosphate level J:211773
increased heart weight J:211773
increased total retina thickness J:211773
Tbl1xr1tm1b(EUCOMM)Hmgu/Tbl1xr1tm1b(EUCOMM)Hmgu
C57BL/6N-Tbl1xr1tm1b(EUCOMM)Hmgu/Ieg 		preweaning lethality, incomplete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory