Mcat Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
MGI:2388651

51 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mcat^tm1.1Ssmi/Mcat^tm1.1Ssmi A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/A1cf⁺ involves: 129P2/OlaHsd C57BL/6 * FVB/N	no abnormal phenotype detected	J:192213
Mcat^tm1.1Ssmi/Mcat^tm1.1Ssmi Tg(CAG-cre/Esr1)5Amc/0 involves: 129P2/OlaHsd C57BL/6 * C57BL/6J * CBA	abnormal cellular respiration	J:192213
	abnormal circulating alanine transaminase level	J:192213
	abnormal coat appearance	J:192213
	abnormal eating behavior	J:192213
	abnormal erythrocyte physiology	J:192213
	abnormal gait	J:192213
	abnormal immune system organ morphology	J:192213
	abnormal lipid homeostasis	J:192213
	abnormal mitochondrial physiology	J:192213
	abnormal muscle physiology	J:192213
	abnormal myelopoiesis	J:192213
	abnormal reticulocyte morphology	J:192213
	alopecia	J:192213
	anemia	J:192213
	normal behavior/neurological phenotype	J:192213
	decreased body temperature	J:192213
	decreased body weight	J:192213
	decreased erythrocyte cell number	J:192213
	decreased exploration in new environment	J:192213
	decreased grip strength	J:192213
	decreased hematocrit	J:192213
	decreased hemoglobin content	J:192213
	decreased leukocyte cell number	J:192213
	decreased locomotor activity	J:192213
	decreased lymphocyte cell number	J:192213
	decreased subcutaneous adipose tissue amount	J:192213
	decreased vertical activity	J:192213
	decreased white adipose tissue amount	J:192213
	normal digestive/alimentary phenotype	J:192213
	dry skin	J:192213
	enlarged spleen	J:192213
	excessive scratching	J:192213
	extramedullary hematopoiesis	J:192213
	hyperkeratosis	J:192213
	impaired exercise endurance	J:192213
	increased circulating chloride level	J:192213
	increased circulating glucose level	J:192213
	increased circulating ketone body level	J:192213
	increased circulating lactate level	J:192213
	increased mean corpuscular volume	J:192213
	increased pruritus	J:192213
	increased red blood cell distribution width	J:192213
	increased skeletal muscle glycogen level	J:192213
	kyphosis	J:192213
	premature death	J:192213
	rectal hemorrhage	J:192213
	rectal prolapse	J:192213
	reticulocytosis	J:192213
	tremors	J:192213
	weight loss	J:192213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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