About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fras1
Fraser extracellular matrix complex subunit 1
MGI:2385368
63 phenotypes from 6 alleles in 9 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Fras1b2b3323Clo/Fras1b2b3323Clo
C57BL/6J-Fras1b2b3323Clo
abnormal digit morphology J:175213
abnormal eye morphology J:175213
absent kidney J:175213
micrognathia J:175213
perimembraneous ventricular septal defect J:175213
Fras1bfb/Fras1bfb
involves: C3H/HeH * C57BL/6JAnu
absent kidney J:199856
bleb J:199856
cleft secondary palate J:199856
eyelids open at birth J:199856
preaxial polydactyly J:199856
Fras1bfb/Fras1bfb
involves: C57BL/6JAnu
abnormal palatal shelf fusion at midline J:208682
abnormal palatal shelf morphology J:208682
abnormal rib morphology J:208682
abnormal sternebra morphology J:208682
abnormal sternum morphology J:208682
absent kidney J:208682
bleb J:208682
blistering J:208682
cleft secondary palate J:208682
complete cleft palate J:208682
normal craniofacial phenotype J:208682
narrow eye opening J:208682
preaxial polydactyly J:208682
small kidney J:208682
subcutaneous hemorrhage J:208682
Fras1bl/Fras1bl
involves: 101/H * C3H/HeH
abnormal basement membrane morphology J:83745
abnormal hair growth J:13501
abnormal kidney development J:83745
abnormal metanephric mesenchyme morphology J:83745
abnormal metanephros morphology J:83745
abnormal ureteric bud morphology J:83745
absent kidney J:13501, J:83745
bleb J:13501
clubfoot J:13501, J:83745
cryptophthalmos J:83745
delayed kidney development J:83745
fetal bleb J:83745
impaired branching involved in ureteric bud morphogenesis J:83745
increased metanephric mesenchyme apoptosis J:83745
kidney cyst J:83745
microphthalmia J:13501
prenatal lethality, incomplete penetrance J:83745
single kidney J:13501, J:83745
small kidney J:83745
syndactyly J:83745
Fras1bl/Fras1tm1.2Pjsc
involves: 101/H * C3H/HeH * C57BL/6 * FVB/N * SJL
abnormal glomerular capillary morphology J:190659
abnormal glomerular capsule space morphology J:190659
abnormal glomerular mesangium morphology J:190659
abnormal renal glomerulus morphology J:190659
cortical renal glomerulopathies J:190659
glomerulosclerosis J:190659
normal integument phenotype J:190659
normal renal/urinary system phenotype J:190659
Fras1rdf/Fras1rdf
involves: C57BL/6J * FVB/NJ
abnormal digit morphology J:231083
abnormal eye morphology J:231083
abnormal hindlimb morphology J:231083
abnormal interdigital cell death J:231083
abnormal limb morphology J:231083
abnormal tail tip morphology J:231083
absent kidney J:231083
blistering J:231083
cleft palate J:231083
decreased body size J:231083
eyelids open at birth J:231083
flaky skin J:231083
postnatal growth retardation J:231083
postnatal lethality, complete penetrance J:231083
preaxial polydactyly J:231083
short tail J:231083
single kidney J:231083
syndactyly J:231083
Fras1tm1.2Pjsc/Fras1tm1.2Pjsc
involves: C57BL/6 * FVB/N * SJL
absent kidney J:190659
blistering J:190659
hemorrhage J:190659
Fras1tm1Chpk/Fras1tm1Chpk
involves: 129S1/Sv * 129X1/SvJ * C57BL/10
absent kidney J:83746
blistering J:83746
cryptophthalmos J:83746
lethality throughout fetal growth and development, complete penetrance J:83746
lethality throughout fetal growth and development, incomplete penetrance J:83746
syndactyly J:83746
Fras1tm1Chpk/Fras1tm1Chpk
involves: 129S1/Sv * 129X1/SvJ * NMRI
abnormal basement membrane morphology J:137010
abnormal lung development J:137010
abnormal lung epithelium morphology J:137010
abnormal lung morphology J:137010
abnormal lung vasculature morphology J:137010
fused right lung lobes J:137010

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory