L2hgdh Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

L2hgdh
L-2-hydroxyglutarate dehydrogenase
MGI:2384968

16 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
L2hgdh^em1(IMPC)Tcp/L2hgdh^em1(IMPC)Tcp C57BL/6N-L2hgdh^em1(IMPC)Tcp/Tcp	abnormal eye morphology	J:211773
	cataract	J:211773
	decreased exploration in new environment	J:211773
	male infertility	J:211773
L2hgdh^{Gt(DC0625)Wtsi}/L2hgdh^{Gt(DC0625)Wtsi} involves: 129P2/OlaHsd * C57BL/6	abnormal amino acid level	J:228407
	abnormal brain morphology	J:228407
	abnormal glial cell morphology	J:228407
	abnormal habituation	J:228407
	abnormal myelin sheath morphology	J:228407
	abnormal oligodendrocyte morphology	J:228407
	abnormal spatial working memory	J:228407
	fatigue	J:228407
	impaired spatial learning	J:228407
	increased locomotor activity	J:228407
	increased susceptibility to pharmacologically induced seizures	J:228407
	increased vertical activity	J:228407

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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