Taf4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Taf4
TATA-box binding protein associated factor 4
MGI:2152346

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Taf4^tm1.1Idvd/Taf4^tm1.1Idvd Not Specified	decreased fibroblast apoptosis	J:125257
	embryonic lethality during organogenesis, complete penetrance	J:125257
	increased fibroblast proliferation	J:125257
Taf4^tm1Idvd/Taf4^tm1Idvd Tg(KRT14-cre)1Ipc/0 Not Specified	impaired skin barrier function	J:124111
	neonatal lethality, complete penetrance	J:124111
	thin skin	J:124111
	translucent skin	J:124111
	weight loss	J:124111
Taf4^tm1Idvd/Taf4^tm1Idvd Tg(KRT14-cre/ERT2)1Ipc/0 involves: C57BL/6 * SJL	abnormal coat/ hair morphology	J:124111
	abnormal hair cycle	J:124111
	abnormal hair shaft morphology	J:124111
	abnormal skin condition	J:124111
	abnormal skin morphology	J:124111
	abnormal tail morphology	J:124111
	chronic inflammation	J:124111
	dermal cyst	J:124111
	dry skin	J:124111
	epidermal hyperplasia	J:124111
	impaired skin barrier function	J:124111
	increased incidence of tumors by chemical induction	J:124111
	increased keratinocyte proliferation	J:124111
	increased malignant tumor incidence	J:124111
	increased squamous cell carcinoma incidence	J:124111
	kinked tail	J:124111
	scaly skin	J:124111
	sparse hair	J:124111

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23