Pds5b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pds5b
PDS5 cohesin associated factor B
MGI:2140945

50 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pds5b^tm1.2Alos/Pds5b^tm1.2Alos involves: 129S2/SvPas	abnormal cell nucleus morphology	J:205601
	abnormal chromosome morphology	J:205601
	abnormal mitosis	J:205601
	aneuploidy	J:205601
	decreased brown adipose tissue amount	J:205601
	decreased cell proliferation	J:205601
	prenatal lethality, incomplete penetrance	J:205601
Pds5b^tm1Jmi/Pds5b^tm1Jmi involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal axial skeleton morphology	J:124279
	abnormal chin morphology	J:124279
	abnormal craniofacial bone morphology	J:124279
	abnormal enteric nervous system morphology	J:124279
	abnormal facial morphology	J:124279
	abnormal heart morphology	J:124279
	abnormal hyoid bone morphology	J:124279
	abnormal long bone morphology	J:124279
	abnormal palatal shelf fusion at midline	J:124279
	abnormal palate bone morphology	J:124279
	abnormal sternum ossification	J:124279
	abnormal superior cervical ganglion morphology	J:124279
	abnormal sympathetic postganglionic fiber morphology	J:124279
	abnormal vertebrae development	J:124279
	cleft secondary palate	J:124279
	complete atrioventricular septal defect	J:124279
	cyanosis	J:124279
	decreased birth body size	J:124279
	decreased germ cell number	J:124279
	decreased male germ cell number	J:124279
	decreased rib number	J:124279
	delayed bone ossification	J:124279
	fetal growth retardation	J:124279
	lethality throughout fetal growth and development, incomplete penetrance	J:124279
	microcephaly	J:124279
	neonatal lethality, complete penetrance	J:124279
	ostium secundum atrial septal defect	J:124279
	palatal shelves fail to meet at midline	J:124279
	pallor	J:124279
	perimembraneous ventricular septal defect	J:124279
	respiratory distress	J:124279
	rib fusion	J:124279
	short chin	J:124279
	short humerus	J:124279
	short limbs	J:124279
	short mandible	J:124279
	short radius	J:124279
	short scapula	J:124279
	short snout	J:124279
	short sternum	J:124279
	short ulna	J:124279
	thin upper lip	J:124279
	ventricular septal defect	J:124279

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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