Pip4k2b Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
MGI:1934234

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Pip4k2a^tm1.2Lca/Pip4k2a⁺ Pip4k2b^{Gt(Betageo)1Lca}/Pip4k2b^{Gt(Betageo)1Lca} involves: 129S/SvEv * 129S5/SvEvBrd	decreased body weight	J:205288
	neonatal lethality, incomplete penetrance	J:205288
	postnatal growth retardation	J:205288
Pip4k2a^tm1.2Lca/Pip4k2a^tm1.2Lca Pip4k2b^{Gt(Betageo)1Lca}/Pip4k2b⁺ Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S/SvEv * 129S2/SvPas * 129S5/SvEvBrd	decreased tumor incidence	J:205288
Pip4k2a^tm1.2Lca/Pip4k2a^tm1.2Lca Pip4k2b^{Gt(Betageo)1Lca}/Pip4k2b^{Gt(Betageo)1Lca} involves: 129S/SvEv * 129S5/SvEvBrd	neonatal lethality, complete penetrance	J:205288
Pip4k2b^{Gt(Betageo)1Lca}/Pip4k2b^{Gt(Betageo)1Lca} Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S2/SvPas * 129S5/SvEvBrd	embryonic lethality during organogenesis, complete penetrance	J:205288
	exencephaly	J:205288
	open neural tube	J:205288

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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