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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Erap1
endoplasmic reticulum aminopeptidase 1
MGI:1933403
24 phenotypes from 6 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Erap1tm1.1Gnie/Erap1tm1.1Gnie
involves: 129S6/SvEvTac * C57BL/6
abnormal antigen presentation J:143988
abnormal cytotoxic T cell physiology J:143988
abnormal response to infection J:143988
decreased interferon-gamma secretion J:143988
decreased level of surface class I molecules J:143988
decreased T cell proliferation J:143988
Erap1tm1Dgen/Erap1tm1Dgen
involves: 129P2/OlaHsd * C57BL/6
enlarged kidney J:101679
enlarged spleen J:101679
extramedullary hematopoiesis J:101679
thymus hyperplasia J:101679
Erap1tm1Iay/Erap1tm1Iay
involves: C57BL/6
abnormal cytotoxic T cell physiology J:111047
decreased level of surface class I molecules J:111047
Erap1tm1Luc/Erap1+
involves: 129S6/SvEvTac
abnormal antigen presentation J:122479
decreased level of surface class I molecules J:122479
Erap1tm1Luc/Erap1tm1Luc
involves: 129S6/SvEvTac
abnormal antigen presentation J:122479
abnormal CD8-positive, alpha-beta T cell physiology J:122479
abnormal lymphocyte physiology J:122479
decreased level of surface class I molecules J:122479
normal immune system phenotype J:122479
increased level of surface class I molecules J:122479
Erap1tm1Nsha/Erap1tm1Nsha
B6.129S6-Erap1tm1Nsha
abnormal antigen presentation via MHC class I J:112389, J:116606
abnormal CD8-positive, alpha-beta T cell physiology J:112389, J:116606
abnormal cytokine secretion J:116606
decreased level of surface class I molecules J:112389
Erap1tm2b(EUCOMM)Wtsi/Erap1tm2b(EUCOMM)Wtsi
C57BL/6N-Erap1tm2b(EUCOMM)Wtsi/Kmpc
abnormal liver morphology J:211773
decreased bone mineral content J:211773
decreased circulating serum albumin level J:211773
decreased total body fat amount J:211773
hyperactivity J:211773
increased circulating calcium level J:211773
increased lean body mass J:211773
thrombocytosis J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory