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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pum1
pumilio RNA-binding family member 1
MGI:1931749
15 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pum1em1(IMPC)Mbp/Pum1em1(IMPC)Mbp
C57BL/6NCrl-Pum1em1(IMPC)Mbp/MbpMmucd 		abnormal skin morphology J:211773
abnormal spleen morphology J:211773
decreased body length J:211773
decreased prepulse inhibition J:211773
enlarged spleen J:211773
Pum1Gt(XE002)Byg/Pum1Gt(XE002)Byg
B6.129P2-Pum1Gt(XE002)Byg 		embryonic lethality before implantation, complete penetrance J:226959
Pum1tm1.1Hfl/Pum1tm1.2Hfl
Tg(Ddx4-cre)1Dcas/0
involves: 129 * C57BL/6 * FVB 		increased male germ cell apoptosis J:182280
Pum1tm1.2Hfl/Pum1+
involves: 129 * C57BL/6 * FVB 		increased male germ cell apoptosis J:182280
oligozoospermia J:182280
Pum1tm1.2Hfl/Pum1tm1.2Hfl
involves: 129 * C57BL/6 * FVB 		abnormal spermatogenesis J:182280
decreased body weight J:182280
decreased testis weight J:182280
increased male germ cell apoptosis J:182280
oligozoospermia J:182280
reduced male fertility J:182280
normal reproductive system phenotype J:182280
small seminiferous tubules J:182280
testis hypoplasia J:182280
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory