Recql4 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Recql4
RecQ protein-like 4
MGI:1931028

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apc^Min/Apc⁺ Recql4^tm1Glu/Recql4^tm1Glu involves: 129S7/SvEvBrd * C57BL/6J	increased adenoma incidence	J:97101
	increased colon adenoma incidence	J:97101
	increased tumor growth/size	J:97101
Recql4^tm1.1Brle/Recql4^tm1.1Brle Trp53^tm1Brn/Trp53^tm1Brn Tg(Col2a1-cre)1Bhr/0 involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * SJL/J	abnormal chondrocyte morphology	J:309253
	abnormal long bone epiphyseal plate morphology	J:309253
	abnormal thoracic cage morphology	J:309253
	perinatal lethality, incomplete penetrance	J:309253
	postnatal lethality, complete penetrance	J:309253
Recql4^tm1.1Brle/Recql4^tm1.1Brle Trp53^tm1Brn/Trp53^tm1Brn Tg(Prrx1-cre)1Cjt/0 involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * SJL/J	abnormal chondrocyte morphology	J:309253
	abnormal forelimb morphology	J:309253
	abnormal long bone epiphyseal plate morphology	J:309253
	postnatal lethality, incomplete penetrance	J:309253

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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