Bhlhe22 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bhlhe22
basic helix-loop-helix family, member e22
MGI:1930001

27 phenotypes from 3 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bhlhe22^tm1Gan/Bhlhe22^tm1Gan involves: 129S7/SvEvBrd	abnormal anterior corticospinal tract morphology	J:144066
	abnormal cerebral cortex morphology	J:144066
	abnormal corticospinal tract morphology	J:144066
	abnormal motor neuron morphology	J:144066
	abnormal nervous system tract morphology	J:144066
	abnormal pyramidal decussation morphology	J:144066
	abnormal somatosensory cortex morphology	J:144066
	decreased body weight	J:144066
	decreased brain size	J:144066
	disorganized barrel cortex	J:144066
Bhlhe22^tm1Gan/Bhlhe22^tm1Gan involves: 129S7/SvEvBrd * C57BL/6	abnormal retina cone bipolar cell morphology	J:119663
	decreased amacrine cell number	J:119663
	decreased body weight	J:119663
	skin lesions	J:119663
	thin retina inner nuclear layer	J:119663
Bhlhe22^tm1Meg/Bhlhe22^tm1Meg either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6) or (involves: 129/Sv * CD-1)	abnormal behavior	J:158273
	abnormal chemical nociception	J:158273
	abnormal nervous system physiology	J:158273
	abnormal sensory capabilities/reflexes/nociception	J:158273
	excessive scratching	J:158273
	skin lesions	J:158273
Bhlhe22^tm1Meg/Bhlhe22^tm1Meg involves: 129S6/SvEvTac * C57BL/6J	abnormal anterior corticospinal tract morphology	J:182304
	abnormal axon guidance	J:182304
	abnormal motor coordination/balance	J:182304
	absent anterior commissure	J:182304
	absent corpus callosum	J:182304
	absent hippocampal commissure	J:182304
	excessive scratching	J:182304
	normal nervous system phenotype	J:182304
	skin lesions	J:182304
Bhlhe22^tm2.1Meg/Bhlhe22^tm2.1Meg Emx1^tm1(cre)Krj/Emx1⁺ involves: 129/Sv * 129S2/SvPas	normal behavior/neurological phenotype	J:158273
	normal integument phenotype	J:158273
Bhlhe22^tm2.1Meg/Bhlhe22^tm2.1Meg Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J	abnormal anterior corticospinal tract morphology	J:182304
	absent corpus callosum	J:182304
	absent hippocampal commissure	J:182304
Bhlhe22^tm2.1Meg/Bhlhe22^tm2.1Meg H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129/Sv * C57BL/6J * CBA/J	abnormal chemical nociception	J:158273
	excessive scratching	J:158273
	skin lesions	J:158273
Bhlhe22^tm2.1Meg/Bhlhe22^tm2.1Meg Tg(Nes-cre)1Kln/0 involves: 129/Sv * C57BL/6 * SJL	excessive scratching	J:158273
	skin lesions	J:158273
Bhlhe22^tm2.1Meg/Bhlhe22^tm2.1Meg Tg(Pax2-cre)1Akg/0 involves: 129	abnormal chemical nociception	J:158273
	excessive scratching	J:158273
	skin lesions	J:158273
Bhlhe22^tm2.1Meg/Bhlhe22^tm2.1Meg Tg(PLAT-cre)116Sdu/0 involves: 129	normal behavior/neurological phenotype	J:158273
	normal integument phenotype	J:158273
Bhlhe22^tm2.1Meg/Bhlhe22^tm2.1Meg Tlx3^tm1(cre)Qima/Tlx3⁺ involves: 129	normal behavior/neurological phenotype	J:158273
	normal integument phenotype	J:158273

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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