Mtor Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mtor
mechanistic target of rapamycin kinase
MGI:1928394

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
\Cdh5^{tm4(Cdh5/Fkbp,Ptprb/Mtor)Dvst}/\Cdh5^{tm4(Cdh5/Fkbp,Ptprb/Mtor)Dvst} involves: C57BL/6	abnormal cellular extravasation	J:178759
	decreased vascular permeability	J:178759
	impaired neutrophil recruitment	J:178759
\Eif4ebp1^tm1Nso/\Eif4ebp1^tm1Nso \Mtor^tm1.1Gcon/\Mtor^tm1.1Gcon \A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/\A1cf⁺ involves: 129S4/SvJae C57BL/6 * FVB/N	abnormal autophagy	J:163763
	abnormal mitochondrial physiology	J:163763
	cardiac interstitial fibrosis	J:163763
	normal cardiovascular system phenotype	J:163763
	decreased cardiomyocyte apoptosis	J:163763
	premature death	J:163763
\Mtor^chino/\Mtor^chino \Rasgrp1^m1Anu/\Rasgrp1^m1Anu involves: C57BL/6JAnu * C57BL/6JSfdAnu * CBA/J	normal hematopoietic system phenotype	J:207898
	normal immune system phenotype	J:207898
\Mtor^{Gt(OST92090)Lex}/\Mtor⁺ \Pten^tm1Rps/\Pten⁺ involves: 129S1/Sv * 129S5/SvEvBrd * C57BL/6	extended life span	J:144810

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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