Ptges Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptges
prostaglandin E synthase
MGI:1927593

6 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gins4^tm1Ntak/Gins4⁺ Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0 Tg(Krt19-Wnt1)2Maos/0 involves: 129P2/OlaHsd * C3H * C57BL/6	decreased tumor growth/size	J:209708
Hmga1^tm1Mina/Hmga1^tm1Mina Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0 Tg(Krt19-Wnt1)2Maos/0 involves: C3H * C57BL/6 * CBA	increased stomach tumor incidence	J:153058
Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0 involves: C3H * C57BL/6	gastric metaplasia	J:116782
Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0 Tg(Krt19-Wnt1)2Maos/0 involves: C3H * C57BL/6	abnormal stomach glandular epithelium morphology	J:116782
	decreased tumor-free survival time	J:116782
	gastric metaplasia	J:116782
	increased gastric adenocarcinoma incidence	J:116782
	increased stomach tumor incidence	J:116782, J:153058

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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