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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fbxo43
F-box protein 43
MGI:1926053
11 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fbxo43tm1.1Kald/Fbxo43tm1.1Kald
Tg(Stra8-icre)1Reb/0
involves: 129 * C57BL/6 * FVB/NJ * SJL 		arrest of male meiosis J:251984
increased male germ cell apoptosis J:251984
male infertility J:251984
Fbxo43tm1.1Kald/Fbxo43tm1.2Kald
Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL 		increased male germ cell apoptosis J:251984
male infertility J:251984
Fbxo43tm1.2Kald/Fbxo43tm1.2Kald
involves: 129 * C57BL/6 * FVB/N * SJL 		abnormal female meiosis J:251984
abnormal oocyte morphology J:251984
arrest of male meiosis J:251984
azoospermia J:251984
decreased testis weight J:251984
female infertility J:251984
increased male germ cell apoptosis J:251984
male infertility J:251984
normal neoplasm J:251984
parthenogenesis J:251984
small testis J:251984
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory