Notum Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Notum
notum palmitoleoyl-protein carboxylesterase
MGI:1924833

46 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Notum^em1(IMPC)Tcp/Notum⁺ C57BL/6NCrl-Notum^em1(IMPC)Tcp/Tcp	abnormal uterus morphology	J:211773
	cataract	J:211773
	decreased exploration in new environment	J:211773
	decreased grip strength	J:211773
	small ovary	J:211773
	small spleen	J:211773
	small uterus	J:211773
Notum^em1(IMPC)Tcp/Notum^em1(IMPC)Tcp C57BL/6NCrl-Notum^em1(IMPC)Tcp/Tcp	abnormal brain morphology	J:211773
	abnormal kidney morphology	J:211773
	anophthalmia	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Notum^em150Sinn/Notum^em150Sinn Not Specified	abnormal bronchus morphology	J:260471
	abnormal kidney development	J:260471
	abnormal trachea development	J:260471
	abnormal trachea morphology	J:260471
	abnormal tracheal cartilage morphology	J:260471
	abnormal tracheal smooth muscle morphology	J:260471
	decreased tracheal cartilage ring number	J:260471
	perinatal lethality	J:260471
	trachea stenosis	J:260471
Notum^{Gt(OST172035)Lex}/Notum⁺ involves: 129S5/SvEvBrd * C57BL/6	increased bone mineral density	J:274615
	increased bone strength	J:274615
	increased compact bone thickness	J:274615
Notum^{Gt(OST172035)Lex}/Notum^{Gt(OST172035)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal cementum morphology	J:266040
	abnormal dentin development	J:266040
	abnormal dentin morphology	J:274615
	abnormal molar morphology	J:274615
	abnormal molar root morphology	J:266040
	abnormal odontoblast morphology	J:266040
	abnormal periodontal ligament morphology	J:266040
	anemia	J:274615
	apical tooth abscess	J:266040
	carious teeth	J:266040
	chronic inflammation	J:274615
	decreased body fat mass	J:274615
	decreased body weight	J:274615
	decreased lean body mass	J:274615
	dental pulp necrosis	J:266040
	increased bone mineral density	J:274615
	increased bone strength	J:274615
	increased compact bone thickness	J:274615
	increased femur compact bone thickness	J:274615
	increased kidney weight	J:266040
	increased lean body mass	J:266040
	increased leukocyte cell number	J:274615
	periodontium inflammation	J:266040
	postnatal lethality, incomplete penetrance	J:266040
	single kidney	J:266040
	normal skeleton phenotype	J:274615

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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