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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sdccag8
serologically defined colon cancer antigen 8
MGI:1924066
50 phenotypes from 4 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sdccag8em1Lji/Sdccag8em1Lji
involves: C57BL/6 		abnormal kidney morphology J:328191
abnormal photoreceptor connecting cilium morphology J:328191
abnormal primary cilium morphology J:328191
abnormal retina cone cell outer segment morphology J:328191
abnormal retina photoreceptor morphology J:328191
absent kidney epithelial cell primary cilium J:328191
decreased a-wave amplitude J:328191
decreased b-wave amplitude J:328191
decreased body weight J:328191
enlarged kidney J:328191
increased retina apoptosis J:328191
increased urine protein level J:328191
kidney cortex cyst J:328191
kidney corticomedullary cyst J:328191
male infertility J:328191
neonatal lethality, incomplete penetrance J:328191
polycystic kidney J:328191
postnatal growth retardation J:328191
preaxial polydactyly J:328191
prenatal lethality, incomplete penetrance J:328191
renal fibrosis J:328191
retina cone cell degeneration J:328191
retina photoreceptor degeneration J:328191
retina rod cell degeneration J:328191
short photoreceptor outer segment J:328191
thin retina outer nuclear layer J:328191
Sdccag8em2Lji/Sdccag8em2Lji
involves: C57BL/6 		abnormal kidney epithelial cell primary cilium morphology J:328191
abnormal kidney morphology J:328191
abnormal photoreceptor connecting cilium morphology J:328191
abnormal primary cilium morphology J:328191
abnormal retina photoreceptor morphology J:328191
decreased a-wave amplitude J:328191
decreased b-wave amplitude J:328191
decreased body weight J:328191
decreased kidney epithelial cell primary cilium length J:328191
enlarged kidney J:328191
increased retina apoptosis J:328191
increased urine protein level J:328191
kidney cortex cyst J:328191
male infertility J:328191
neonatal lethality, incomplete penetrance J:328191
postnatal growth retardation J:328191
preaxial polydactyly J:328191
prenatal lethality, incomplete penetrance J:328191
renal fibrosis J:328191
retina photoreceptor degeneration J:328191
retina rod cell degeneration J:328191
short photoreceptor outer segment J:328191
thin retina outer nuclear layer J:328191
Sdccag8Gt(OST40418)Lex/Sdccag8Gt(OST40418)Lex
involves: 129S5/SvEvBrd * C57BL/6J 		abnormal DNA replication J:226661
abnormal electroretinogram waveform feature J:226661
abnormal kidney corticomedullary boundary morphology J:226661
abnormal kidney morphology J:226661
abnormal retina photoreceptor morphology J:226661
blindness J:226661
normal cellular phenotype J:226661
decreased retina cone cell number J:226661
dilated renal tubule J:226661
enlarged kidney J:226661
kidney cortex cyst J:226661
kidney corticomedullary cyst J:226661
kidney cyst J:226661
photoreceptor inner segment degeneration J:226661
photoreceptor outer segment degeneration J:226661
renal glomerulus cyst J:226661
renal interstitial fibrosis J:226661
normal renal/urinary system phenotype J:226661
retina degeneration J:226661
retina outer nuclear layer degeneration J:226661
retina photoreceptor degeneration J:226661
Sdccag8tm1e(EUCOMM)Wtsi/Sdccag8tm1e(EUCOMM)Wtsi
involves: C57BL/6 		abnormal choroid plexus morphology J:215665
abnormal neuronal migration J:215665
abnormal nonmotile primary cilium morphology J:215665
cleft palate J:215665
enlarged lateral ventricles J:215665
polydactyly J:215665
postnatal lethality, incomplete penetrance J:215665
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory