Fads1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fads1
fatty acid desaturase 1
MGI:1923517

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fads1^{Gt(IST11525H2)Tigm}/Fads1⁺ C57BL/6-Fads1^{Gt(IST11525H2)Tigm}	abnormal enterocyte proliferation	J:186265
	decreased interferon-gamma secretion	J:186265
	decreased prostaglandin level	J:186265
	decreased tumor necrosis factor secretion	J:186265
	increased prostaglandin level	J:186265
Fads1^{Gt(IST11525H2)Tigm}/Fads1^{Gt(IST11525H2)Tigm} C57BL/6-Fads1^{Gt(IST11525H2)Tigm}	abnormal circulating lipid level	J:186265
	abnormal enterocyte proliferation	J:186265
	abnormal lipid level	J:186265
	abnormal mononuclear cell morphology	J:186265
	decreased interferon-gamma secretion	J:186265
	decreased prostaglandin level	J:186265
	decreased regulatory T cell number	J:186265
	decreased tumor necrosis factor secretion	J:186265
	increased prostaglandin level	J:186265
	increased susceptibility to xenobiotic induced morbidity/mortality	J:186265
	premature death	J:186265
Fads1^{tm1.1(KOMP)Vlcg}/Fads1^{tm1.1(KOMP)Vlcg} C57BL/6N-Fads1^{tm1.1(KOMP)Vlcg}/Ucd	abnormal testis morphology	J:211773
	decreased body length	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating triglyceride level	J:211773
	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	decreased total body fat amount	J:211773
	improved glucose tolerance	J:211773
	increased bone mineral content	J:211773
	increased brain weight	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating phosphate level	J:211773
	increased kidney weight	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	small testis	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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