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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tmem43
transmembrane protein 43
MGI:1921372
13 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tmem43em1Cby/Tmem43+
involves: 129 * C57BL/6J 		abnormal auditory brainstem response waveform shape J:314357
abnormal organ of Corti supporting cell morphology J:314357
normal cardiovascular system phenotype J:314357
conductive hearing loss J:314357
decreased auditory brainstem response wave amplitude J:314357
decreased cochlear inner hair cell number J:314357
normal hearing/vestibular/ear phenotype J:314357
increased or absent threshold for auditory brainstem response J:314357
Tmem43em1Cby/Tmem43em1Cby
involves: 129 * C57BL/6J 		conductive hearing loss J:314357
Tmem43Gt(OST62799)Lex/Tmem43Gt(OST62799)Lex
involves: 129S5/SvEvBrd * C57BL/6J 		increased anxiety-related response J:94077
Tmem43tm1.1Xlin/Tmem43+
involves: 129 * C57BL/6 * FVB/N 		abnormal adipose tissue amount J:289209
abnormal myofibroblast differentiation J:289209
cardiac fibrosis J:289209
normal cardiovascular system phenotype J:289209
decreased heart left ventricle posterior wall thickness J:289209
normal immune system phenotype J:289209
increased heart left ventricle size J:289209
increased heart weight J:289209
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory