Tmem43^{Gt(OST62799)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Tmem43^{Gt(OST62799)Lex}
• Name: transmembrane protein 43; gene trap OST62799, Lexicon Genetics
• MGI ID: MGI:4168877
• Gene: Tmem43 Location: Chr6:91450689-91465445 bp, + strand Genetic Position: Chr6, 40.54 cM, cytoband D2
• Alliance: Tmem43^{Gt(OST62799)Lex} page

Mutation origin

• Mutant Cell Line: OST62799
• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The Tmem43 gene consists of 12 exons. Retroviral insertion disrupted the gene in the intron between coding exons 1 and 2 (NCBI accession NM_028766.1). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:94077)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST62799	CG510841 ; (MGI Seq Detail)	3' RACE	Chr6:91454224-91455311 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  7 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tmem43 Mutation: 30 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)