Cep55 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cep55
centrosomal protein 55
MGI:1921357

47 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cep55^em1(IMPC)Tcp/Cep55⁺ C57BL/6NCrl-Cep55^em1(IMPC)Tcp/Tcp	abnormal ovary morphology	J:211773
	abnormal sternum morphology	J:211773
	cataract	J:211773
	small kidney	J:211773
	small uterus	J:211773
Cep55^em1(IMPC)Tcp/Cep55^em1(IMPC)Tcp C57BL/6NCrl-Cep55^em1(IMPC)Tcp/Tcp	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Cep55^em1.1Hyli/Cep55^em1.1Hyli involves: C57BL/6	abnormal brain ventricle morphology	J:313163
	abnormal cell cycle	J:313163
	abnormal choroid plexus morphology	J:313163
	abnormal dorsal striatum morphology	J:313163
	abnormal embryonic neuroepithelium primary cilium morphology	J:313163
	abnormal hippocampus morphology	J:313163
	abnormal primary cilium morphology	J:313163
	abnormal thalamus morphology	J:313163
	normal craniofacial phenotype	J:313163
	decreased cell proliferation	J:313163
	dilated lateral ventricle	J:313163
	dilated third ventricle	J:313163
	enlarged brain ventricles	J:313163
	hydrocephaly	J:313163
	increased brain ependyma motile cilium length	J:313163
	increased kidney epithelial cell primary cilium length	J:313163
	kidney cyst	J:313163
	normal limbs/digits/tail phenotype	J:313163
	postnatal lethality, complete penetrance	J:313163
	renal glomerulus cyst	J:313163
	small cerebellum	J:313163
	thin cerebral cortex	J:313163
Cep55^{tm1a(EUCOMM)Hmgu}/Cep55^{tm1a(EUCOMM)Hmgu} involves: C57BL/6N	abnormal cerebral cortex morphology	J:287102
	abnormal cranium morphology	J:287102
	abnormal kidney cortex morphology	J:287102
	abnormal mitotic cytokinesis	J:287102
	abnormal motor capabilities/coordination/movement	J:287102
	abnormal renal glomerulus morphology	J:287102
	absent gastric milk in neonates	J:287102
	decreased body weight	J:287102
	decreased brain size	J:287102
	decreased brain weight	J:287102
	decreased cerebral cortex cell density	J:287102
	decreased neuronal precursor cell number	J:287102
	increased cell nucleus count	J:287102
	increased neuron apoptosis	J:287102
	microcephaly	J:287102
	pallor	J:287102
	postnatal lethality, incomplete penetrance	J:287102
	thin cerebral cortex	J:287102
Cep55^{tm1c(EUCOMM)Hmgu}/Cep55^{tm1c(EUCOMM)Hmgu} Gt(ROSA)26Sor^{tm9(cre/ESR1)Arte}/Gt(ROSA)26Sor⁺ involves: C57BL/6N * C57BL/6NTac	increased cell nucleus count	J:287102
Cep55^{tm1c(EUCOMM)Hmgu}/Cep55^{tm1c(EUCOMM)Hmgu} Tg(Vil1-cre)20Syr/0 involves: C57BL/6N * DBA/2	normal digestive/alimentary phenotype	J:287102

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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