Ythdf1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ythdf1
YTH N6-methyladenosine RNA binding protein 1
MGI:1917431

18 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ythdf1^em1Chhe/Ythdf1^em1Chhe B6.Cg-Ythdf1^em1Chhe	abnormal excitatory postsynaptic potential	J:267186
	abnormal hippocampus pyramidal cell morphology	J:267186
	abnormal miniature excitatory postsynaptic currents	J:267186
	abnormal paired-pulse ratio	J:267186
	abnormal spatial reference memory	J:267186
	abnormal translation	J:267186
	normal behavior/neurological phenotype	J:267186
	decreased dendritic spine density	J:267186
	impaired contextual conditioning behavior	J:267186
	impaired spatial learning	J:267186
	impaired synaptic plasticity	J:267186
	normal nervous system phenotype	J:267186
	reduced long-term potentiation	J:267186
Ythdf1^em2Jhha/Ythdf1^em2Jhha involves: BALB/c * C57BL/6	normal embryo phenotype	J:299108
	normal mortality/aging	J:299108
	normal reproductive system phenotype	J:299108
Ythdf1^tm1.1Sjj/Ythdf1^tm1.1Sjj Tg(Atoh1-cre/Esr1*)14Fsh/0 involves: FVB/N	abnormal axon guidance	J:276416
	abnormal protein level	J:276416

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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