Prss21 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prss21
serine protease 21
MGI:1916698

29 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prss21^{em1(IMPC)Ccpcz}/Prss21⁺ C57BL/6N-Prss21^{em1(IMPC)Ccpcz}/Ccpcz	abnormal heart morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spine curvature	J:211773
	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	abnormal uterus morphology	J:211773
	enlarged heart	J:211773
	enlarged thymus	J:211773
	hydrometra	J:211773
	increased circulating total protein level	J:211773
	kyphosis	J:211773
	lordosis	J:211773
	wrinkled skin	J:211773
Prss21^{em1(IMPC)Ccpcz}/Prss21^{em1(IMPC)Ccpcz} C57BL/6N-Prss21^{em1(IMPC)Ccpcz}/Ccpcz	preweaning lethality, complete penetrance	J:211773
Prss21^tm1Anta/Prss21^tm1Anta involves: NIH Black Swiss	abnormal sperm flagellum morphology	J:154521
	abnormal sperm head morphology	J:154521
	abnormal sperm physiology	J:154521
	abnormal spermatogenesis	J:154521
	coiled sperm flagellum	J:154521
	decreased fertilization frequency	J:154521
	decreased sperm progressive motility	J:154521
	detached sperm flagellum	J:154521
	hairpin sperm flagellum	J:154521
	impaired fertilization	J:154521
	oligozoospermia	J:154521
	teratozoospermia	J:154521
Prss21^tm1Tba/Prss21^tm1Tba involves: 129S2/SvPas * ICR	impaired acrosome reaction	J:142458
	impaired binding of sperm to zona pellucida	J:142458
	impaired fertilization	J:142458
	impaired sperm penetration of zona pellucida	J:142458

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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