Insig1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Insig1
insulin induced gene 1
MGI:1916289

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Insig1^{em1(IMPC)Ccpcz}/Insig1^{em1(IMPC)Ccpcz} C57BL/6N-Insig1^{em1(IMPC)Ccpcz}/Ccpcz	abnormal cholesterol homeostasis	J:211773
	abnormal maxilla morphology	J:211773
	abnormal urinary bladder morphology	J:211773
	decreased body weight	J:211773
	decreased circulating chloride level	J:211773
	decreased locomotor activity	J:211773
	impaired glucose tolerance	J:211773
	increased aggression	J:211773
	increased fasting circulating glucose level	J:211773
	increased freezing behavior	J:211773
	increased mean corpuscular hemoglobin	J:211773
Insig1^tm1.1Aztc/Insig1^tm1.1Aztc Not Specified	abnormal white fat cell differentation	J:208931
	abnormal white fat cell morphology	J:208931
	normal behavior/neurological phenotype	J:208931
	decreased body length	J:208931
	decreased body weight	J:208931
	decreased circulating triglyceride level	J:208931
	normal homeostasis/metabolism phenotype	J:208931
	increased gonadal fat pad weight	J:208931
	increased subcutaneous adipose tissue amount	J:208931
Insig1^tm1Mbjg/Insig1^tm1Mbjg Tg(Mx1-cre)29-4Her/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl * SJL	normal homeostasis/metabolism phenotype	J:101203

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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