Hint2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hint2
histidine triad nucleotide binding protein 2
MGI:1916167

26 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Hint2^tm1.1Geno/Hint2^tm1.1Geno involves: 129S2/SvPas * C57BL/6J	abnormal body temperature homeostasis	J:237329
	abnormal enzyme/coenzyme activity	J:237329
	abnormal hepatocyte physiology	J:237329
	abnormal liver morphology	J:237329
	abnormal mitochondrial morphology	J:237329
	abnormal mitochondrial physiology	J:237329
	abnormal respiratory electron transport chain	J:237329
	abnormal retroperitoneal fat pad morphology	J:237329
	decreased circulating glucagon level	J:237329
	decreased circulating triglyceride level	J:237329
	decreased insulin secretion	J:237329
	decreased noradrenaline level	J:237329
	impaired glucose tolerance	J:237329
	increased adiponectin level	J:237329
	increased body weight	J:237329
	increased circulating alanine transaminase level	J:237329
	increased circulating cholesterol level	J:237329
	increased circulating corticosterone level	J:237329
	increased circulating insulin level	J:237329
	increased circulating leptin level	J:237329
	increased circulating serum albumin level	J:237329
	increased insulin sensitivity	J:237329
	increased liver triglyceride level	J:237329
	increased liver weight	J:237329
	macrovesicular hepatic steatosis	J:237329
	oxidative stress	J:237329

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23