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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
MGI:1916066
24 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ppil1em1(IMPC)Mbp/Ppil1+
C57BL/6N-Ppil1em1(IMPC)Mbp/MbpMmucd
abnormal kidney morphology J:211773
abnormal skin morphology J:211773
increased circulating creatinine level J:211773
increased startle reflex J:211773
polycystic kidney J:211773
small kidney J:211773
small spleen J:211773
Ppil1em1(IMPC)Mbp/Ppil1em1(IMPC)Mbp
C57BL/6N-Ppil1em1(IMPC)Mbp/MbpMmucd
embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Ppil1em2Jgg/Ppil1em2Jgg
C57BL/6-Ppil1em2Jgg
embryonic lethality, complete penetrance J:300487
Ppil1em2Jgg/Ppil1em3Jgg
C57BL/6-Ppil1em2Jgg Ppil1em3Jgg
decreased embryo size J:300487
Ppil1em3Jgg/Ppil1em3Jgg
C57BL/6-Ppil1em3Jgg
abnormal cerebral cortex morphology J:300487
decreased cerebral cortex average cell area J:300487
decreased forebrain volume J:300487
forebrain hypoplasia J:300487
increased neuron apoptosis J:300487
loss of cortex neurons J:300487
microcephaly J:300487
neonatal lethality, complete penetrance J:300487
thin cerebral cortex J:300487
Ppil1em4Jgg/Ppil1em4Jgg
C57BL/6-Ppil1em4Jgg
increased neuron apoptosis J:300487
loss of cortex neurons J:300487
microcephaly J:300487
perinatal lethality, complete penetrance J:300487
thin cerebral cortex J:300487
Ppil1em5Jgg/Ppil1em5Jgg
C57BL/6-Ppil1em5Jgg
normal mortality/aging J:300487
normal nervous system phenotype J:300487
normal reproductive system phenotype J:300487

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory