About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Eml1
echinoderm microtubule associated protein like 1
MGI:1915769
61 phenotypes from 5 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Eml1em1(IMPC)Wtsi/Eml1em1(IMPC)Wtsi
C57BL/6N-Eml1em1(IMPC)Wtsi/Wtsi
absent pinna reflex J:211773
decreased erythrocyte cell number J:211773
decreased fasting circulating glucose level J:211773
increased mean corpuscular hemoglobin J:211773
Eml1heco/?
involves: CD-1
abnormal brain development J:211342
abnormal cortical intermediate zone morphology J:211342
abnormal mitotic spindle morphology J:211342
abnormal neuronal precursor proliferation J:211342
abnormal radial glial cell morphology J:211342
ectopic neuron J:211342
increased neuron apoptosis J:211342
Eml1heco/Eml1heco
involves: C57BL/6 * NOR
ectopic cortical neuron J:208031
Eml1heco/Eml1heco
involves: NOR
abnormal cortical intermediate zone morphology J:208031
abnormal cranium morphology J:208031
abnormal locomotor activation J:208031
abnormal locomotor behavior J:208031
abnormal righting response J:208031
bradykinesia J:208031
brain atrophy J:208031
decreased body size J:208031
decreased body weight J:208031
decreased locomotor activity J:208031
delayed eyelid opening J:208031
delayed hair appearance J:208031
ectopic cortical neuron J:208031
enlarged brain ventricles J:208031
impaired spatial learning J:208031
increased susceptibility to pharmacologically induced seizures J:208031
myoclonus J:208031
normal nervous system phenotype J:208031
seizures J:208031
thickened cerebral cortex J:208031
Eml1m1Btlr/Eml1m1Btlr
C57BL/6J-Eml1m1Btlr
round head J:272865
Eml1tm1.2Ics/Eml1+
C57BL/6N-Eml1tm1.2Ics
abnormal cortical plate morphology J:294769
abnormal embryonic/fetal subventricular zone morphology J:294769
decreased anterior commissure size J:294769
premature death J:294769
Eml1tm1.2Ics/Eml1tm1.2Ics
C57BL/6N-Eml1tm1.2Ics
abnormal brain morphology J:294769
abnormal cerebral cortex morphology J:294769
abnormal cortical intermediate zone morphology J:294769
abnormal cortical plate morphology J:294769
abnormal cortical ventricular zone morphology J:294769
abnormal dorsal subiculum morphology J:294769
abnormal embryonic/fetal subventricular zone morphology J:294769
abnormal hippocampus CA3 region morphology J:294769
abnormal hippocampus pyramidal cell layer J:294769
abnormal neuronal precursor proliferation J:294769
absent corpus callosum J:294769
decreased anterior commissure size J:294769
decreased cingulate cortex size J:294769
ectopic neuron J:294769
enlarged lateral ventricles J:294769
hydrocephaly J:294769
premature death J:294769
preweaning lethality, incomplete penetrance J:294769
small lateral ventricles J:294769
thin cerebral cortex J:294769
Eml1tvrm360/Eml1tvrm360
C57BL/6J-Eml1tvrm360/Pjn
abnormal cone electrophysiology J:297748
abnormal Muller cell morphology J:297748
abnormal photoreceptor outer segment disc membrane morphology J:297748
abnormal retina development J:297748
abnormal retina horizontal cell morphology J:297748
abnormal retina morphology J:297748
abnormal retina neuronal layer morphology J:297748
abnormal retina progenitor cell morphology J:297748
abnormal rod electrophysiology J:297748
decreased a-wave amplitude J:297748
decreased b-wave amplitude J:297748
dilated lateral ventricle J:297748
ectopic neuron J:297748
obstructive hydrocephaly J:297748
premature death J:297748
preweaning lethality, incomplete penetrance J:297748

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory