Eml1^{em1(IMPC)Wtsi}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Eml1^{em1(IMPC)Wtsi}
• Name: echinoderm microtubule associated protein like 1; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6153330
• Gene: Eml1 Location: Chr12:108337265-108505835 bp, + strand Genetic Position: Chr12, 59.46 cM
• Alliance: Eml1^{em1(IMPC)Wtsi} page
• IMPC: Eml1 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Wellcome Sanger Institute using Cas9 and 4 guides with spacer sequences TGCTATCTAGGGTCATAGTT, TTGTACCCCTGCCACTTTGC, and TTTGAGGCTTGCAGAAGCGC that targeted exon(s) ENSMUSE00001305609.2. This resulted in deletion(s) of 405 bp (location: Chr12:108437994-108438398; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Eml1 Mutation: 46 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 5 reference(s)