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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tmem70
transmembrane protein 70
MGI:1915068
28 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tmem70em2(IMPC)Bay/Tmem70+
C57BL/6N-Tmem70em2(IMPC)Bay/Bay
abnormal embryo size J:211773
abnormal embryo turning J:211773
embryonic growth retardation J:211773
increased grip strength J:211773
Tmem70em2(IMPC)Bay/Tmem70em2(IMPC)Bay
C57BL/6N-Tmem70em2(IMPC)Bay/Bay
abnormal embryo development J:211773
abnormal embryo size J:211773
abnormal embryo turning J:211773
abnormal neural tube morphology J:211773
abnormal pharyngeal arch morphology J:211773
abnormal somite shape J:211773
embryonic growth retardation J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Tmem70tm1a(KOMP)Wtsi/Tmem70+
involves: C57BL/6N
normal cellular phenotype J:238642
decreased ventricle muscle contractility J:238642
normal growth/size/body region phenotype J:238642
normal homeostasis/metabolism phenotype J:238642
Tmem70tm1a(KOMP)Wtsi/Tmem70tm1a(KOMP)Wtsi
involves: C57BL/6N
abnormal enzyme/coenzyme level J:238642
abnormal mitochondrial crista morphology J:238642
abnormal mitochondrial physiology J:238642
abnormal mitochondrial shape J:238642
abnormal oxidative phosphorylation J:238642
decreased embryo size J:238642
delayed embryo turning J:238642
delayed heart development J:238642
delayed rostral neuropore closure J:238642
delayed somite formation J:238642
disorganized mitochondrial cristae J:238642
embryonic growth retardation J:238642
embryonic lethality during organogenesis, complete penetrance J:238642
oxidative stress J:238642
small heart J:238642
Tmem70tm1b(KOMP)Wtsi/Tmem70tm1b(KOMP)Wtsi
involves: C57BL/6N * C57BL/6NTac
embryonic lethality during organogenesis, complete penetrance J:238642

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory