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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gadd45gip1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
MGI:1914947
33 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gadd45gip1tm1Kong/Gadd45gip1tm1Kong
involves: 129P2/OlaHsd * C57BL/6 		absent inner cell mass proliferation J:156583
absent proamniotic cavity J:156583
decreased cell proliferation J:156583
decreased embryo size J:156583
embryonic growth retardation J:156583
embryonic lethality between implantation and somite formation, complete penetrance J:156583
increased embryonic tissue cell apoptosis J:156583
Gadd45gip1tm1Kong/Gadd45gip1tm2Kong
involves: 129P2/OlaHsd * C57BL/6 		abnormal cell physiology J:156583
Gadd45gip1tm2Kong/Gadd45gip1tm2Kong
Tg(Ins2-cre)25Mgn/0
involves: 129P2/OlaHsd * C57BL/6 * DBA 		abnormal mitochondrial crista morphology J:220742
abnormal mitochondrial matrix morphology J:220742
abnormal mitochondrial morphology J:220742
abnormal mitochondrial physiology J:220742
abnormal pancreatic beta cell morphology J:220742
abnormal pancreatic beta cell physiology J:220742
abnormal pancreatic islet morphology J:220742
decreased insulin secretion J:220742
decreased oxygen consumption J:220742
decreased pancreatic beta cell mass J:220742
decreased pancreatic beta cell number J:220742
decreased pancreatic beta cell proliferation J:220742
impaired glucose tolerance J:220742
increased mitochondrial number J:220742
Gadd45gip1tm2Kong/Gadd45gip1tm2Kong
Tg(Vil1-cre)997Gum/0
involves: 129P2/OlaHsd * C57BL/6J * SJL 		abnormal digestive system development J:156319
abnormal enterocyte morphology J:156319
abnormal small intestinal crypt cell proliferation J:156319
abnormal small intestinal microvillus morphology J:156319
abnormal small intestinal villus morphology J:156319
decreased small intestinal villus height J:156319
decreased small intestinal villus number J:156319
normal digestive/alimentary phenotype J:156319
perinatal lethality, incomplete penetrance J:156319
postnatal lethality, incomplete penetrance J:156319
prenatal lethality, incomplete penetrance J:156319
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory