Wdr45b Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Wdr45b
WD repeat domain 45B
MGI:1914090

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atg7^tm1Tchi/Atg7^tm1Tchi Tg(Nes-cre)1Kln/0 Wdr45b^{tm1c(EUCOMM)Hmgu}/Wdr45b^{tm1c(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * SJL	abnormal axon morphology	J:298097
	abnormal cerebellar granule cell morphology	J:298097
	abnormal endoplasmic reticulum morphology	J:298097
	abnormal Golgi apparatus morphology	J:298097
	cerebellum atrophy	J:298097
	impaired coordination	J:298097
	lethality during fetal growth through weaning, complete penetrance	J:298097
	postnatal growth retardation	J:298097
	prenatal lethality, incomplete penetrance	J:298097
	Purkinje cell degeneration	J:298097

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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