Spag16 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Spag16
sperm associated antigen 16
MGI:1913972

16 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Spag16^tm1Jfs/Spag16⁺ chimera involves: 129/Sv * C57BL/6J	abnormal outer dense fiber morphology	J:92446
	abnormal seminiferous tubule morphology	J:92446
	abnormal Sertoli cell morphology	J:92446
	abnormal sperm axoneme morphology	J:92446
	abnormal sperm motility	J:92446
	abnormal spermatogenesis	J:92446
	absent sperm axonemal central pair	J:92446
	arrest of spermatogenesis	J:92446
	increased male germ cell apoptosis	J:92446
	kinked sperm flagellum	J:92446
	male infertility	J:92446
	oligozoospermia	J:92446
	seminiferous tubule degeneration	J:92446
	small testis	J:92446
Spag16^tm2Jfs/Spag16⁺ involves: 129S6/SvEvTac	abnormal spermatogenesis	J:107006
Spag16^tm2Jfs/Spag16^tm2Jfs involves: 129S6/SvEvTac	asthenozoospermia	J:107006
	male infertility	J:107006
	small testis	J:107006
	teratozoospermia	J:107006

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/07/2025 MGI 6.24