Ppdpf Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
MGI:1913746

11 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppdpf^{tm1.1(KOMP)Mbp}/Ppdpf^{tm1.1(KOMP)Mbp} C57BL/6N-Ppdpf^{tm1.1(KOMP)Mbp}/MbpMmucd	preweaning lethality, incomplete penetrance	J:211773
Ppdpf^tm1Nju/Ppdpf^tm1Nju Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * DBA	hepatic steatosis	J:307283
	impaired glucose tolerance	J:307283
	increased body weight	J:307283
	increased circulating free fatty acids level	J:307283
	increased circulating triglyceride level	J:307283
	increased lipogenesis	J:307283
	increased liver triglyceride level	J:307283
	increased liver weight	J:307283
	increased susceptibility to diet-induced hepatic steatosis	J:307283
	insulin resistance	J:307283

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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