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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ctsz
cathepsin Z
MGI:1891190
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ctsbtm1Jde/Ctsbtm1Jde
Ctsztm1Thre/Ctsztm1Thre
FVB.129P2-Ctsztm1Thre Ctsbtm1Jde 		no abnormal phenotype detected J:157541
Ctsbtm1Jde/Ctsbtm1Jde
Ctsztm1Thre/Ctsztm1Thre
Tg(MMTV-PyVT)634Mul/0
FVB.129P2-Ctsztm1Thre Ctsbtm1Jde Tg(MMTV-PyVT)634Mul 		abnormal tumor morphology J:157541
decreased apoptosis J:157541
decreased metastatic potential J:157541
decreased tumor growth/size J:157541
increased mammary gland tumor incidence J:157541
increased tumor latency J:157541
Ctsztm1Thre/Ctsztm1Thre
Tg(MMTV-PyVT)634Mul/0
FVB.129P2-Ctsztm1Thre Tg(MMTV-PyVT)634Mul 		decreased apoptosis J:157541
decreased metastatic potential J:157541
increased mammary gland tumor incidence J:157541
increased tumor growth/size J:157541
increased tumor latency J:157541
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory