Elp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Elp2
elongator acetyltransferase complex subunit 2
MGI:1889642

37 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Elp2^em1Bjw/Elp2^em2Bjw involves: C57BL/6	decreased fetal size	J:306113
	embryonic lethality during organogenesis, incomplete penetrance	J:306113
	lethality throughout fetal growth and development, complete penetrance	J:306113
Elp2^em1Bjw/Elp2^em3Bjw involves: C57BL/6	decreased embryo size	J:306113
Elp2^em1Bjw/Elp2^em3Bjw involves: C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:306113
Elp2^em2Bjw/Elp2^em2Bjw involves: C57BL/6	abnormal anterior commissure morphology	J:306113
	abnormal brain internal capsule morphology	J:306113
	abnormal forebrain morphology	J:306113
	abnormal gait	J:306113
	abnormal hypothalamus morphology	J:306113
	decreased body length	J:306113
	decreased body weight	J:306113
	decreased grip strength	J:306113
	decreased neocortex volume	J:306113
	hypotonia	J:306113
	increased grooming behavior	J:306113
	lethality at weaning, complete penetrance	J:306113
	limb grasping	J:306113
	microcephaly	J:306113
	postnatal growth retardation	J:306113
	tremors	J:306113
Elp2^em2Bjw/Elp2^em2Bjw involves: C57BL/6 * DBA/2J	abnormal brain commissure morphology	J:306113
	abnormal brain interneuron morphology	J:306113
	abnormal brain white matter morphology	J:306113
	abnormal cortical plate morphology	J:306113
	abnormal dendrite morphology	J:306113
	abnormal gait	J:306113
	abnormal neuron differentiation	J:306113
	abnormal somatosensory cortex morphology	J:306113
	cerebellum atrophy	J:306113
	decreased body length	J:306113
	decreased body weight	J:306113
	decreased dendritic spine density	J:306113
	decreased grip strength	J:306113
	decreased neuronal precursor cell number	J:306113
	decreased vocalization	J:306113
	hypotonia	J:306113
	increased grooming behavior	J:306113
	limb grasping	J:306113
	microcephaly	J:306113
	postnatal growth retardation	J:306113
	premature death	J:306113
	Purkinje cell degeneration	J:306113
	thin cerebral cortex	J:306113
	tremors	J:306113
Elp2^em2Bjw/Elp2^em3Bjw involves: C57BL/6	decreased fetal size	J:306113
	hemorrhage	J:306113
	lethality during fetal growth through weaning, complete penetrance	J:306113
Elp2^em2Bjw/Elp2^em3Bjw involves: C57BL/6 * DBA/2J	abnormal gait	J:306113
	cerebellum atrophy	J:306113
	decreased body length	J:306113
	decreased body weight	J:306113
	decreased grip strength	J:306113
	decreased vocalization	J:306113
	hypotonia	J:306113
	increased grooming behavior	J:306113
	limb grasping	J:306113
	microcephaly	J:306113
	premature death	J:306113
	Purkinje cell degeneration	J:306113
	tremors	J:306113
Elp2^em3Bjw/Elp2^em3Bjw involves: C57BL/6	decreased embryo size	J:306113
Elp2^em3Bjw/Elp2^em3Bjw involves: C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:306113

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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