Atp8b1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atp8b1
ATPase, class I, type 8B, member 1
MGI:1859665

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atp8b1^tm1Nbf/Atp8b1^tm1Nbf Por^tm1Wolf/Por^tm1Wolf Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA	abnormal bile salt homeostasis	J:215915
	abnormal bile secretion	J:215915
	bile duct proliferation	J:215915
	cholestasis	J:215915
	increased bile salt level	J:215915
	increased circulating alanine transaminase level	J:215915
	increased circulating alkaline phosphatase level	J:215915
	increased circulating bilirubin level	J:215915
	increased liver weight	J:215915
	increased susceptibility to induced morbidity/mortality	J:215915
	weight loss	J:215915

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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