Atoh7 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atoh7
atonal bHLH transcription factor 7
MGI:1355553

24 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atoh7^{tm1.1(Ascl1)Nlbr}/Atoh7⁺ Tg(Atoh7-cre)360Gla/0 Tg(CAG-Bgeo/GFP)21Lbe/0 either: (involves: 129 * C57BL/6 * FVB/N * SJL) or (involves: 129 * C57BL/6 * CD-1 * FVB/N * SJL)	abnormal retina development	J:203642
	decreased retina rod cell number	J:203642
Atoh7^{tm1.1(Ascl1)Nlbr}/Atoh7^{tm1.1(Ascl1)Nlbr} Tg(Atoh7-cre)360Gla/0 Tg(CAG-Bgeo/GFP)21Lbe/0 either: (involves: 129 * C57BL/6 * FVB/N * SJL) or (involves: 129 * C57BL/6 * CD-1 * FVB/N * SJL)	abnormal cell cycle	J:203642
	abnormal retina progenitor cell morphology	J:203642
	decreased retina ganglion cell number	J:203642
	increased retina apoptosis	J:203642
	increased retina cone cell number	J:203642
Atoh7^tm1Gan/Atoh7^tm1Gan Pou4f2^tm1Nat/Pou4f2^tm1Nat B6.Cg-Pou4f2^tm1Nat Atoh7^tm1Gan	abnormal eye electrophysiology	J:135827
	abnormal Muller cell morphology	J:135827
	abnormal retina ganglion cell morphology	J:135827
	abnormal retina morphology	J:135827
	abnormal retina rod bipolar cell morphology	J:135827
	decreased amacrine cell number	J:135827
	decreased retina ganglion cell number	J:135827
	increased retina apoptosis	J:135827
	retina hypoplasia	J:135827
	thin retina ganglion layer	J:135827
	thin retina inner nuclear layer	J:135827
	thin retina outer nuclear layer	J:135827
Atoh7^tm1Gla/Atoh7^tm1Gla Tg(Crx-Atoh7,-cre)60Gla/0 Gt(ROSA)26Sor^tm1Sho/Gt(ROSA)26Sor⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * SJL	abnormal optic nerve innervation	J:186563
	abnormal retina nerve fiber layer morphology	J:186563
Atoh7^tm1Gla/Atoh7^tm1Gla Tg(Crx-Atoh7,-cre)251Gla/0 Gt(ROSA)26Sor^tm1Sho/Gt(ROSA)26Sor⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * SJL	abnormal optic nerve innervation	J:186563
	abnormal optic nerve morphology	J:186563
	abnormal retina ganglion layer morphology	J:186563
	abnormal retina nerve fiber layer morphology	J:186563
Atoh7^tm2Gan/Atoh7^tm2Gan Neurod1^{tm1.1(Atoh7)Whk}/Neurod1^{tm1.1(Atoh7)Whk} Not Specified	abnormal optic nerve morphology	J:194077
	abnormal rod electrophysiology	J:194077
	abnormal sensory neuron innervation pattern	J:194077
	decreased retina ganglion cell number	J:194077
Atoh7^tm2Gan/Atoh7^tm2Gan Rest^tm1.1Whk/Rest^tm1.1Whk Tg(Six3-cre)69Frty/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * DBA/2	abnormal retina development	J:167071
	abnormal retina morphology	J:167071
Fat3^tm1.2Good/Fat3^tm1.2Good Atoh7^tm3(cre)Gan/Atoh7^tm3(cre)Gan involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J	abnormal retina neuronal layer morphology	J:176668

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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