Atoh7^tm3(cre)Gan
Targeted Allele Detail

Summary

• Symbol: Atoh7^tm3(cre)Gan
• Name: atonal bHLH transcription factor 7; targeted mutation 3, Lin Gan
• MGI ID: MGI:3514047
• Synonyms: Math5-cre
• Gene: Atoh7 Location: Chr10:62935564-62937059 bp, + strand Genetic Position: Chr10, 32.54 cM
• Alliance: Atoh7^tm3(cre)Gan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86669
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Atoh7^tm3(cre)Gan expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Atoh7 (MGI:1355553)

• Mutation details: A Cre recombinase coding region was fused immediately upstream of the translation initiation codon and replaced the endogenous coding sequence. Cre expression was then under the control of the endogenous gene promoter. (J:86669)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh7 (mouse) Summary of all recombinase alleles driven by Atoh7. Alliance mouse Atoh7 gene page

Expression

In Mice Carrying this Mutation:

11 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atoh7 Mutation: 9 strains or lines available

References

• Original: J:86669 Yang Z, et al., Math5 determines the competence state of retinal ganglion cell progenitors. Dev Biol. 2003 Dec 1;264(1):240-54
• All: 20 reference(s)