All Phenotypes Atoh7<tm3(cre)Gan> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Atoh7^tm3(cre)Gan
targeted mutation 3, Lin Gan
MGI:3514047

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atoh7^tm3(cre)Gan/Atoh7^tm3(cre)Gan	involves: 129S7/SvEvBrd * C57BL/6J	MGI:3717726
cx2	Fat3^tm1.2Good/Fat3^tm1.2Good Atoh7^tm3(cre)Gan/Atoh7^tm3(cre)Gan	involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J	MGI:5295431

Allelic Composition	Atoh7^tm3(cre)Gan/Atoh7^tm3(cre)Gan
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atoh7^tm3(cre)Gan mutation (0 available); any Atoh7 mutation (9 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

decreased retina ganglion cell number ( J:86669 , J:176668 )

• severe loss of retinal ganglion cells similar to that seen in other Atoh7 null mice (J:86669)

vision/eye

vision/eye phenotype ( J:176668 )

N	• no ectopic plexiform layers form

decreased retina ganglion cell number ( J:86669 , J:176668 )

• severe loss of retinal ganglion cells similar to that seen in other Atoh7 null mice (J:86669)

Allelic Composition	Fat3^tm1.2Good/Fat3^tm1.2Good Atoh7^tm3(cre)Gan/Atoh7^tm3(cre)Gan
Genetic Background	involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atoh7^tm3(cre)Gan mutation (0 available); any Atoh7 mutation (9 available)
Fat3^tm1.2Good mutation (0 available); any Fat3 mutation (240 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal retina neuronal layer morphology ( J:176668 )

• amacrine cells form two additional plexiform layers (inner and outer misplaced plexiform layers) compared with wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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