Nckap1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nckap1
NCK-associated protein 1
MGI:1355333

24 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nckap1^{Gt(RRQ139)Byg}/Nckap1^{Gt(RRQ139)Byg} involves: 129P2/OlaHsd * C3H	abnormal anterior visceral endoderm cell migration	J:166095
	abnormal cell migration	J:173526
	increased apoptosis	J:173526
Nckap1^Gt(XE068)Byg/Nckap1^Gt(XE068)Byg involves: 129P2/OlaHsd	abnormal allantois morphology	J:119028
	abnormal developmental patterning	J:119028
	abnormal digestive system development	J:119028
	abnormal heart development	J:119028
	abnormal neural tube morphology	J:119028
	abnormal somite development	J:119028
	embryonic growth arrest	J:119028
	embryonic lethality during organogenesis, complete penetrance	J:119028
	rostral-caudal axis duplication	J:119028
Nckap1^Gt(XE133)Byg/Nckap1^Gt(XE133)Byg involves: 129P2/OlaHsd	abnormal allantois morphology	J:119028
	abnormal developmental patterning	J:119028
	abnormal digestive system development	J:119028
	abnormal heart development	J:119028
	abnormal neural tube morphology	J:119028
	abnormal somite development	J:119028
	embryonic growth arrest	J:119028
	embryonic lethality during organogenesis, complete penetrance	J:119028
	rostral-caudal axis duplication	J:119028
Nckap1^khlo/Nckap1^khlo C3Fe.B6-Nckap1^khlo	abnormal allantois morphology	J:119028
	abnormal anterior visceral endoderm cell migration	J:119028
	abnormal endoderm development	J:119028
	abnormal foregut morphology	J:119028
	abnormal mesoderm development	J:119028
	abnormal paraxial mesoderm morphology	J:119028
	abnormal primitive streak formation	J:119028
	abnormal primitive streak morphology	J:119028
	cardia bifida	J:119028
	decreased somite size	J:119028
	embryonic growth arrest	J:119028
	embryonic lethality during organogenesis, complete penetrance	J:119028
	failure of chorioallantoic fusion	J:119028
	open neural tube	J:119028
	rostral-caudal axis duplication	J:119028
Nckap1^khlo/Nckap1^khlo involves: C3HeB/FeJ * C57BL/6J	decreased somite size	J:98216
	embryonic growth arrest	J:98216
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:98216
	incomplete embryo turning	J:98216

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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