Exosc10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Exosc10
exosome component 10
MGI:1355322

24 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Exosc10^em1Dean/Exosc10^em1Dean involves: C57BL/6J * DBA/2J	abnormal blastocyst formation	J:293856
	abnormal oocyte morphology	J:293856
	decreased litter size	J:293856
	decreased oocyte number	J:293856
	reduced female fertility	J:293856
Exosc10^tm1.1Vlcg/Exosc10^tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac	no abnormal phenotype detected	J:200671
Exosc10^{tm1a(KOMP)Wtsi}/Exosc10^{tm1c(KOMP)Wtsi} Tg(Gdf9-icre)5092Coo/0 involves: C57BL/6 * C57BL/6N	abnormal estrous cycle	J:369950
	abnormal oocyte morphology	J:369950
	abnormal oogenesis	J:369950
	abnormal ovary morphology	J:369950
	abnormal polar body morphology	J:369950
	absent corpus luteum	J:369950
	absent secondary ovarian follicles	J:369950
	absent tertiary ovarian follicles	J:369950
	decreased oocyte number	J:369950
	decreased primordial ovarian follicle number	J:369950
	embryonic growth arrest	J:369950
	female infertility	J:369950
	impaired ovarian folliculogenesis	J:369950
	increased atretic ovarian follicle number	J:369950
	increased secondary ovarian follicle number	J:369950
	oocyte degeneration	J:369950
	ovary cyst	J:369950
	prenatal lethality, incomplete penetrance	J:369950
	prolonged metestrus	J:369950
	small ovary	J:369950

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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