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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Podxl
podocalyxin-like
MGI:1351317
22 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Podxlem1(IMPC)H/Podxl+
C57BL/6N-Podxlem1(IMPC)H/H
abnormal retina morphology J:211773
Podxlem1(IMPC)H/Podxlem1(IMPC)H
C57BL/6N-Podxlem1(IMPC)H/H
preweaning lethality, complete penetrance J:211773
Podxltm1Kmn/Podxl+
either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)
omphalocele J:70294
Podxltm1Kmn/Podxltm1Kmn
either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)
absent podocyte foot process J:70294
absent podocyte slit diaphragm J:70294
anuria J:70294
hydrops fetalis J:70294
increased systemic arterial blood pressure J:70294
neonatal lethality, complete penetrance J:70294
omphalocele J:70294
Podxltm1Parl/Podxl+
Tg(Mylpf-cre)3Kraj/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N
no abnormal phenotype detected J:158322
Podxltm1Parl/Podxltm1Parl
Tg(Mylpf-cre)3Kraj/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N
abnormal capillary morphology J:158322
abnormal carotid artery morphology J:158322
enlarged brain ventricles J:158322
Podxltm2Kmn/Podxltm2Kmn
B6.129(SJL)-Podxltm2Kmn
no abnormal phenotype detected J:223453
Podxltm2Kmn/Podxltm2Kmn
Tg(Cdh5-cre)7Mlia/0
B6.Cg-Podxltm2Kmn Tg(Cdh5-cre)7Mlia
abnormal lung morphology J:223453
abnormal lung volume J:223453
abnormal pulmonary collagen fibril morphology J:223453
abnormal pulmonary elastic fiber morphology J:223453
decreased lung endothelial cell adhesion J:223453
increased airway resistance J:223453
increased lung endothelial cell adhesion J:223453
increased vascular permeability J:223453
overexpanded pulmonary alveolus J:223453

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory