Podxl^tm1Parl
Targeted Allele Detail

Summary

• Symbol: Podxl^tm1Parl
• Name: podocalyxin-like; targeted mutation 1, Roberto Parrilla
• MGI ID: MGI:4442892
• Synonyms: Podxl^floxed
• Gene: Podxl Location: Chr6:31496428-31540872 bp, - strand Genetic Position: Chr6, 12.57 cM
• Alliance: Podxl^tm1Parl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158322
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 5. A floxed neo cassette was inserted downstream for exon 7. Cre-mediated recombination removed the neo cassette and left exons 5 through 7 floxed. (J:178107)

Expression

In Mice Carrying this Mutation:	30 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Podxl Mutation: 16 strains or lines available

References

• Original: J:158322 Nowakowski A, et al., Ventricular enlargement associated with the panneural ablation of the podocalyxin gene. Mol Cell Neurosci. 2010 Jan;43(1):90-7
• All: 3 reference(s)