Figla Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Figla
folliculogenesis specific basic helix-loop-helix
MGI:1349421

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Figla^tm1Dean/Figla^tm1Dean involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal double-strand DNA break repair	J:294629
	abnormal female meiosis	J:294629
	abnormal female meiosis I arrest	J:294629
	abnormal oogenesis	J:294629
	abnormal ovarian folliculogenesis	J:64677
	absent primordial ovarian follicles	J:64677
	decreased oocyte number	J:64677
	female infertility	J:64677
	increased female germ cell apoptosis	J:294629
	increased ovary apoptosis	J:294629
	normal reproductive system phenotype	J:64677
	small ovary	J:64677
Tg(TSPY1-Figla)#Dean/? FVB/N-Tg(TSPY1-Figla)#Dean	abnormal male germ cell morphology	J:162655
	abnormal sperm motility	J:162655
	abnormal spermatocyte morphology	J:162655
	arrest of male meiosis	J:162655
	decreased male germ cell number	J:162655
	impaired fertilization	J:162655
	kinked sperm flagellum	J:162655
	male infertility	J:162655
	oligozoospermia	J:162655
	seminiferous tubule degeneration	J:162655
	small testis	J:162655

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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