Sdc2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sdc2
syndecan 2
MGI:1349165

13 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sdc2^{tm1b(KOMP)Wtsi}/Sdc2^{tm1b(KOMP)Wtsi} C57BL/6N-Sdc2^{tm1b(KOMP)Wtsi}/Ieg	abnormal coat/hair pigmentation	J:211773
	abnormal lens morphology	J:211773
	aorta stenosis	J:211773
	decreased red blood cell distribution width	J:211773
	decreased total retina thickness	J:211773
	increased circulating triglyceride level	J:211773
Sdc2^{tm1c(KOMP)Wtsi}/Sdc2^{tm1c(KOMP)Wtsi} Tg(Cdh5-cre/ERT2)1Rha/0 involves: C57BL/6J * C57BL/6N	decreased angiogenesis	J:276769
	decreased susceptibility to injury	J:276769
Sdc2^{tm1c(KOMP)Wtsi}/Sdc2^{tm1c(KOMP)Wtsi} Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 involves: C57BL/6J * C57BL/6N * CBA	abnormal retina vasculature morphology	J:276769
	decreased angiogenesis	J:276769
	decreased endothelial cell proliferation	J:276769
	decreased vascular endothelial cell proliferation	J:276769
Sdc2^{tm1d(KOMP)Wtsi}/Sdc2^{tm1d(KOMP)Wtsi} involves: C57BL/6J * C57BL/6N	abnormal retina vasculature morphology	J:276769
	abnormal vascular endothelial cell physiology	J:276769
	decreased angiogenesis	J:276769
	decreased vascular endothelial cell proliferation	J:276769
	delayed wound healing	J:276769

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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