37 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Krastm1Bbd/Kras+ Mapk14tm1Nbr/Mapk14tm2Nbr Polr2atm1(cre/ERT2)Bbd/Polr2a+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	abnormal lung development	J:122397
	abnormal tumor incidence	J:122397
	enlarged lung	J:122397
	increased lung adenocarcinoma incidence	J:122397
	increased lung adenoma incidence	J:122397
	increased lung tumor incidence	J:122397
	premature death	J:122397
Krastm1Bbd/Kras+ Mapk14tm2Nbr/Mapk14+ Polr2atm1(cre/ERT2)Bbd/Polr2a+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	increased hemolymphoid system tumor incidence	J:122397
	increased lung adenoma incidence	J:122397
	increased lung tumor incidence	J:122397
	premature death	J:122397
Mapk11tm1Jda/Mapk11tm1Jda Mapk14tm1Jda/Mapk14tm1Jda involves: 129 * C57BL/6	abnormal T-helper 1 cell differentiation	J:165966
	abnormal T-helper 2 cell differentiation	J:165966
	abnormal T-helper 17 cell differentiation	J:165966
	decreased interferon-gamma secretion	J:165966
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:165966
	decreased susceptibility to induced arthritis	J:165966
	decreased T cell proliferation	J:165966
	decreased tumor necrosis factor secretion	J:165966
	increased interleukin-10 secretion	J:165966
Mapk11tm1Jsca/Mapk11+ Mapk14tm2Nbr/Mapk14tm2Nbr Edil3Tg(Sox2-cre)1Amc/Edil3+ involves: 129P2/OlaHsd * C57BL/6 * CBA	primary sex reversal	J:191096
Mapk11tm1Jsca/Mapk11tm1Jsca Mapk14tm2Nbr/Mapk14tm2Nbr Edil3Tg(Sox2-cre)1Amc/Edil3+ involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal fetal cardiomyocyte proliferation	J:176023
	abnormal liver morphology	J:176023
	abnormal neuron proliferation	J:176023
	exencephaly	J:176023
	increased hepatocyte apoptosis	J:176023
	lethality throughout fetal growth and development, complete penetrance	J:176023
	primary sex reversal	J:191096
	small liver	J:176023
	spina bifida	J:176023
	ventricular septal defect	J:176023
Mapk11tm1Jsca/Mapk11tm1Jsca Mapk14tm2Nbr/Mapk14tm3.1(Mapk11)Nbr Edil3Tg(Sox2-cre)1Amc/Edil3+ involves: 129P2/OlaHsd * C57BL/6 * CBA	normal nervous system phenotype	J:176023
	postnatal lethality, complete penetrance	J:176023
	ventricular septal defect	J:176023
Mapk14tm1.1Dvb/Mapk14+ Ppm1dtm1Lad/Ppm1dtm1Lad involves: 129S7/SvEvBrd * C57BL/6	normal cellular phenotype	J:151980
Mapk14tm1.1Dvb/Mapk14+ Ppm1dtm1Lad/Ppm1dtm1Lad Tg(IghMyc)22Bri/0 involves: 129S7/SvEvBrd * C57BL * FVB/N * SJL	decreased tumor incidence	J:120284
	premature death	J:120284
Mapk14tm2Nbr/Mapk14tm3.1(Mapk11)Nbr Edil3Tg(Sox2-cre)1Amc/Edil3+ involves: C57BL/6 * CBA	postnatal lethality, incomplete penetrance	J:176023
Mapk14tm3.1(Mapk11)Nbr/Mapk14tm3.1(Mapk11)Nbr Not Specified	abnormal trophoblast layer morphology	J:176023
	decreased placental labyrinth size	J:176023
	embryonic growth retardation	J:176023
	prenatal lethality, complete penetrance	J:176023
Ppp3cbtm1Jmk/Ppp3cbtm1Jmk Tg(Myh6-Mapk14*)1Jmol/0 involves: 129S6/SvEvTac * C57BL/6 * FVB	normal cardiovascular system phenotype	J:83547